Cryptococcus neoformansas a Model for Radioimmunotherapy of Infections
نویسندگان
چکیده
منابع مشابه
Cryptococcus neoformans as a Model for Radioimmunotherapy of Infections
There is an obvious and urgent need for novel approaches to treat infectious diseases. The use of monoclonal antibodies in therapy of infectious diseases is now experiencing renewed interest. During the last 5 years radioimmunotherapy (RIT), a modality previously developed only for cancer treatment, has been successfully adapted for the treatment of experimental fungal, bacterial, and viral inf...
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15 صفحه اولRadioimmunotherapy of Cryptococcus neoformans spares bystander mammalian cells.
AIM Previously, we showed that radioimmunotherapy (RIT) for cryptococcal infections using radioactively labeled antibodies recognizing the cryptococcal capsule reduced fungal burden and prolonged survival of mice infected with Cryptococcus neoformans. Here, we investigate the effects of RIT on bystander mammalian cells. MATERIALS & METHODS Heat-killed C. neoformans bound to anticapsular antib...
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ژورنال
عنوان ژورنال: Interdisciplinary Perspectives on Infectious Diseases
سال: 2011
ISSN: 1687-708X,1687-7098
DOI: 10.1155/2011/830286